DNA is the name given to the molecules that contain our genes. The genes on the DNA contain the production information of the proteins necessary for our life. The genes on the DNA carry the characteristics of that person and enable them to be passed on to the next generations.
DNA is made up of twin chains and there are bonds between these chains. Breaks in the DNA region in the cell nucleus in the head of the sperm affect sperm functions. These breaks are called fragmentation.
What Are the Effects of Sperm DNA Fragmentation?
- Decreased fertilization rate during IVF,
- Slow embryo development
- Recurrent IVF failures,
- Unexplained infertility and
- Recurrent pregnancy loss is one of the main negative effects
Causes and treatment of sperm DNA fragmentation
- Cigarettes and alcohol,
- Environmental factors such as radiation and chemicals,
- Nutrition habits,
- Infections and
- Varicocele can cause this discomfort.
DNA fragmentation is not routinely looked at in sperm analysis. Special methods are used for this. Sperm DNA damage rate of 30% and above is considered significant. This damage; It can be reduced by treating infections, not smoking and not using alcohol, giving anti-oxidant therapy and operating advanced varicoceles.
